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Answers: 2006 Series -  February 14, 2006 Lecture 46 of 52  NEXT»

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Photos courtesy of: Patrick Ma, M.D.
Used with permission. Not to be reproduced.

A 28-year-old Hispanic woman presents with decreased vision and was found to have bilateral granulomatous anterior uveitis, vitritis, and exudative retinal detachments. She has also been complaining of headaches and tinnitus with occasional vertigo.  Interestingly, she has noted vitiligo on her chest and hands.

Most likely this represents:   

b -- Vogt-Koyanagi-Harada (VKH) syndrome

 

Vogt-Koyanagi-Harada (VKH) syndrome

The diagnosis of VKH must include three of the following:

  1. Bilateral chronic anterior uveitis
  2. Posterior uveitis and may be associated with exudative retinal detachments and/or disc edema
  3. Neurologic findings such as headache with neck stiffness (meningitis), encephalopathy, and auditory features (tinnitus, hearing loss, and vertigo)
  4. Cutaneous findings--including alopecia, vitiligo, and/or poliosis

 


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