To see views enlarged, click on the individual pictures...

This 2-year-old Hispanic girl was presented by her mother who was concerned about some discoloration on the white of the eye and in the skin around the eye.  The girl is otherwise healthy and the eye examination, except for the pigmentation shown in the pictures, was normal.  The discoloration of the sclera is "slate grey" and the perilimbal skin appears to have light brown pigmentation

1.	The most likely diagnosis is:
	c -- oculodermal melanocytosis (nevus of Ota)
2.	Which of the following statements are true?
	a -- Patients with this condition should be followed regularly. These patients should be followed regularly because of an increased likelihood of developing uveal melanoma.  The dermal lesion is not likely to become malignant but is thought by some to have the possibility of doing so.  The condition is congenital and does show gender predilection.
3.	This patient's chance of developing a uveal melanoma is:
	c -- greater than the general population Patients with nevus of Ota have a 1:400 chance of developing uveal melanoma compared to 1:13,000 for the general population.