1. Chronic skin diseases, including psoriasis, neurodermatitis, exfoliative dermatitis, ichthyosis, alopecia areata, acne, lichen planus, epidermolysis bullosa, lupus erythematosus, acanthosis nigricans, dermatophytosis, hereditary ectodermal dysplasia syndrome and acrodermatitis
2. Congenital atrichia
3. Cryptophthalmos
4. Cutaneous T cell lymphoma
5. Demodicosis
6. Drugs, including the following:
 

acebutolol(?) acenocoumarin(?) acetazolamide(?) acetohexamide(?) acid bismuth sodium tartrate actinomycin C(?) alcohol(?) allopurinol(?) aluminum nicotinate amantadine(?) aminopterin(?) aminosalicylate(?) aminosalicylic acid(?) amiodarone(?) amithiozone(?) amitriptyline(?) amodiaquine(?) amoxapine(?) amphetamine(?) anisindione(?) aspirin(?) atenolol(?) auranofin(?) aurothioglucose(?) aurothioglycanide(?) azathioprine(?) benzphetamine(?) betaxolol bishydroxycoumarin(?) bismuth oxychloride(?) bismuth sodium tartrate(?) bismuth sodium thioglycollate(?) bismuth sodium triglycollamate(?) bismuth subcarbonate(?) bismuth subsalicylate(?) bleomycin(?) broxyquinoline(?) busulfan(?) cactinomycin captopril(?) carbamazepine(?) carbimazole(?) carmustine CCNU chlorambucil(?) chloroquine(?) chlorphenterrnine(?) chlorpropamide(?) cimetidine(?) cisplatin clofibrate(?) clomiphene(?) clonazepam(?) colchicine(?) cyclophosphamide(?) cytarabine(?) dacarbazine dactinomycin(?) danazol(?) daunorubicin desipramine(?) dextroamphetamine(?) dextrothyroxine(?) diacetylmorphine(?) DIC dichlorphenamide(?) dicumarol(?) diethylcarbamazine diethylpropion(?)

diltiazem(?) diphenadione(?) divalproex sodium(?) doxepin(?) doxorubicin dromostanolone(?) droperidol(?) enalapril(?) epinephrine ergonovine(?) ergotamine(?) ethionamide(?) ethotoin(?) ethoxzolamide(?) ethyl biscoumacetate(?) etretinate(?) fenfluramine(?) fenoprofen(?) flecainide(?) floxuridine(?) fluorouracil(?) fluoxymesterone(?) gentamicin glyburide glycopyrrolate(?) gold au 198 gold sodium thiomalate(?) gold sodium thiosulfate(?) guanethidine(?) haloperidol(?) HCNU heparin(?) hydroxychloroquine(?) hydroxyurea(?) ibuprofen(?) imipramine(?) indomethacin(?) interferon(?) iodochlorhydroxyquin(?) iodoquinol(?) isotretinoin(?) ketoprofen(?) labetalol(?) levobunolol levodopa(?) lithium carbonate(?) lomustine maprotiline(?) mechlorethamine(?) melphalan(?) mephenytoin(?) methamphetamine(?) methazolamide(?) methimazole(?) methotrexate(?) methylergonovine(?) methylthiouracil(?) methysergide(?) metoprolol(?) mexiletine(?) mianserin(?) minocycline(?) minoxidil(?) mitomycin mitotane(?) morphine(?) nadolol(?) naltrexone(?) naproxen(?)

niacin(?) niacinamide(?) nicotinyl alcohol(?) nifedipine(?) nitrofurantoin(?) nortriptyline(?) opium(?) oral contraceptives(?) oxprenolol(?) paramethadione(?) penicillamine(?) phendimetrazine(?) phenindione(?) phenmetrazine(?) phenprocoumon(?) phentermine(?) pindolol(?) pipobroman(?) piroxicam prazosin(?) procarbazine(?) propranolol(?) propylthiouracil(?) protriptyline(?) pyridostigmine(?) ranitidine semustine sodium salicylate(?) streptomycin(?) streptozocin sulfacetamide(?) sulfachlorpyridazine(?) sulfacytine(?) sulfadiazine(?) sulfadimethoxine(?) sulfamerazine(?) sulfameter(?) sulfamethazine(?) sulfamethizole(?) sulfamethoxazole sulfamethoxypyridazine(?) sulfanilamide(?) sulfaphenazole(?) sulfapyridine(?) sulfasalazine(?) sulfathiazole(?) sulfisoxazole sulindac(?) tamoxifen(?) testolactone(?) testosterone(?) tetracycline(?) thiotepa timolol maleate tocainide(?) tolazamide(?) tolbutamide(?) triethylenemelamine(?) trifluperidol(?) trimethadione(?) uracil mustard(?) valproate sodium(?) valproic acid(?) verapamil(?) vinblastine(?) vincristine(?) vitamin A warfarin(?)

7. Ehlers-Danlos syndrome, unspecified type
*8. Endocrine disease, including hypothyroidism, hyperthyroidism, pituitary insufficiency, hypoparathyroidism, and pituitary necrosis syndrome (Simmonds-Sheehan syndrome)
9. Following eyelid tattooing
10. Generalized hypotrichosis
11. HIV (human immunodeficiency virus)
12. Hypocalcemia
13. Hypothermal injury
*14. Idiopathic
15. Inflammation and infection of the lids, including seborrheic blepharitis, squamous blepharitis, herpes zoster, sebaceous gland carcinoma, vaccinia, mycotic infection, furuncles, and erysipelas
16. Intoxication with arsenic, bismuth, thallium, gold, quinine and vitamin A
17. Isolated madarosis
18. Keratosis decalvans
19. Keratosis follicularis
20. Keratosis spinulosa
21. Lid colobomas
22. Leprosy
23. Lipoid proteinosis (Urbach-Wiethe syndrome)
24. Polymorphous light eruption
25. Pseudoprogeria syndrome
26. Radiation
27. Severe debilitating systemic diseases, including tuberculosis, syphilis, sickle cell anemia, cholera, and Hansen disease (leprosy)
28. Trauma
29. Vogt-Koyanagi-Harada disease (uveitis-vitiligo-alopecia-poliosis syndrome)

Extracted Table Madarosis (loss of eyelashes)

Dana MR, et al. Ocular manifestations of leprosy in a noninstitutionalized community in the United States. Arch Ophthalmol 1994; 112:626-629.

Fraunfelder FT, Fraunfelder FW. Drug-induced ocular side effects. Woburn, MA: Butterworth-Heinemann, 200l.

Isenberg SJ. The eye in infancy. Chicago: Year Book Medical, 1989.

Roy FH. Ocular syndromes and systemic diseases, 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2002.