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Conjunctiva -  CICATRICIAL CONJUNCTIVITIS (SCARRING OF CONJUNCTIVA) Lecture 10 of 32  NEXT»

*1. General: a postinfectious type of membranous conjunctivitis such as C. diphtheriae, streptococcal conjunctivitis, autoimmune or presumably autoimmune sarcoidosis, scleroderma, Stevens-Addison, pemphigoid, lichen planus, atopic blepharoconjunctivitis, miscellaneous causes and linear IgA dermatosis.
2. Upper lid

 A. Trachoma

3. Lower lid

 *A. Acne rosacea (ocular rosacea)
 B. Chemical (especially alkali)
 C. Chlamydia organisms (psittacosis-lymphogranuloma group)
 D. Chronic cicatricial conjunctivitis-occurs in the elderly; has a chronic course;  may have concurrent skin and mucous membrane lesions
 *E. Congenital syphilis
 F. Dermatitis herpetiformis
 G. Epidemic keratoconjunctivitis
 H. Epidermolysis acuta toxica (Lyell syndrome)
 I. Epidermolysis bullosa
 *J. Erythema multiforme (Stevens-Johnson disease)
 K. Erythroderma ichthyosiforme
 L. Exfoliative dermatitis
 M. Fuchs-Lyell syndrome
 N. Hydroa vacciniforme
 O. Impetigo
 P. Lamellar ichthyoses
 *Q. Ocular pemphigoid
 R. Paraneoplastic lichen planus
 S. Radium bums
 T. Reiter syndrome (conjunctivourethrosynovial syndrome)
 U. Sjögren syndrome (secretoinhibitor syndrome)
 V. Staphylococcal granuloma
 W. Syphilis (acquired lues)
 X. Systemic scleroderma (progressive systemic sclerosis)
 Y. Vaccinia

*4. Drugs

 A. Demecarium bromide
 *B. Echothiophate iodide
 C. Idoxuridine
 D. Penicillamine
 E. Pilocarpine
 F. Practolol
 G. Thiabendazole
 H. Timolol
 *I. Topical ocular epinephrine

Chan LS, et al. Ocular cicatricial pemphigoid occurring as a sequela of Stevens-Johnson syndrome. JAMA 1991; 266:1543-1546.

Chiou AG, et al. Management of conjunctival cicatrizing diseases and severe ocular surface dysfunction. Surv Ophthalmol 1998; 43:19-46.

Cruz AV, et al. Eyelid abnormalities in lamellar ichthyoses. Ophthalmology 2000; 107:1895-1898.

Fraunfelder FT, Fraunfelder FW. Drug-induced ocular side effects. Woburn, MA: Butterworth-Heinemann, 2001.

Hahn JM, et al. Cicatrizing conjunctivitis associated with paraneoplastic lichen planus. Am J Ophthalmol 2000; 129: 98-99.

Hoang-Xuan T, et al. Epidermolysis bullosa acquisita diagnosed by direct immunoelectron microscopy of the conjunctiva. Ophthalmology 1997; 104:1414-1420.

Hoang-Xuan T, et al. Pure ocular cicatricial pemphigoid. Ophthalmology 1999; 106:355-362.


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