This condition involves a localized conjunctival, limbal, or corneal nodule measuring about 1 to 3 mm.

* 1. Delayed hypersensitivity to bacterial protein, particularly tuberculoprotein and staphylococci; lymphopathia venereum and coccidioidomycosis may also be allergens
2. Malnutrition
3. Secondary infection of the conjunctiva, especially from S. aureus, pneumococcus, and Koch-Weeks bacillus
4. Systemic infection

 A. Bang disease (brucellosis)
 B. Candidiasis
 C. Neurodermatitis
 D. Mikulicz-Radecki syndrome (dacryosialoadenopathy)
 E. Trachoma
 F. Sjögren syndrome (secretoinhibitor syndrome)

Davis PL, Watson JL. Experimental conjunctival phlyctenulosis. Can J Ophthalmol 1969; 4:183-190.

Newell FW. Ophthalmology: principles and concepts, 7th ed. St. Louis: CV Mosby, 1991.